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White Paper
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By reading this white paper you will learn about the challenges associated with the discovery and development of therapeutic antibodies – an especially promising and lucrative field for the biopharmaceutical industry. The white paper discusses the benefits of using large antibody panels for screening and interrogating the epitope diversity of the whole panel in early-stage using Array SPR (Surface Plasmon Resonance) to accelerate discovery. Researchers can now realize the full kinetic and epitope potential of their antibody libraries.
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Here we conduct a study into the behavior and stability of IL-2 using microfluidic diffusional sizing (MDS) in order to observe native state, in-solution responses. The tendency to oligomerize at varying concentrations, and the stability (particularly propensity to aggregate) under changing buffer conditions are investigated.
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Stunner pulls double-duty so you don’t have to. It’s the only system out there that takes UV/Vis concentration and Dynamic Light Scattering (DLS) size measurements from the same sample at the same time. Nail down your protein quality by knocking concentration, hydrodynamic size, polydispersity, and detection of aggregates off your list in one shot. Without skipping a beat, you can also measure the colloidal stability of your samples or design your own custom apps.
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BioData/Labguru
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Labguru is a secure, compliant, web and cloud-based, Electronic Lab Notebook (ELN) that enables biotech, life sciences, and pharma companies, as well as academic institutions, to run their labs more efficiently and maximize their research output. It’s trusted by over 30,000 users worldwide who rely on it to plan and document experiments, track progress, streamline lab logistics and share results.
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Ultra-Low Temperature Freezers
Independent test results confirm the new VIP ECO® upright ultra-low temperature freezer has the lowest total daily energy usage in its class in the industry. Download the white paper to get more details of key performance metrics from independent ENERGY STAR® testing.
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Taking place at a critical juncture in drug and vaccine development, Developmental and Reproductive Toxicology (DART) is a highly specialized science that companies simply cannot afford to get wrong. Getting the science right is extremely critical. Is your DART program subject to critical missteps that will place you at risk of program failure? Here’s how to tell.
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Lonza
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How does the delivery of CRISPR/Cas9 plasmids compare to ribonucleoproteins (RNPs)? A Lonza customer shares a protocol using the non-viral Nucleofector™ Technology for comparing NHEJ and HDR frequencies resulting from CRISPR/Cas9 delivered as plasmids or RNPs. Download the white paper:
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ATCC |
Antibiotic resistance is a serious, globally extensive problem that significantly affects patient morbidity and mortality. Here, we discuss the emerging threat of antibiotic resistance and the importance of clinically relevant reference materials for use in assay development and drug discovery.
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MilliporeSigma
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The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)
system was discovered in bacteria, where it functions as an adaptive
immune system against invading viral and plasmid DNA. In this system,
short DNA sequences (spacers) from invading viruses are incorporated at
CRISPR loci within the bacterial genome and serve as memory of previous
infections.
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Battelle |
Neurobehavioral testing provides critical insights into how drugs and chemicals affect the nervous system. This Whitepaper covers the considerations in the Design and Execution of Neurobehavioral Studies.
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ProZyme
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Glycosylation of biotherapeutics is a frequently monitored critical quality attribute. N-Glycan analysis typically involves release and derivatization to a fluorescent label. Workflow and analysis are impacted by label choice. Click for more
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INTEGRA
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Eppendorf |
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R&D Systems |
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BioTek |
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Hera BioLabs |
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BioTek |
The imaging and analysis of fluorescently stained cells has traditionally been accomplished using manual microscopic methods with low numbers of samples. Here we describe the use of the Lionheart™ FX Automated Live Cell Imager and the CellASIC ONIX2 perfusion micro-incubator to rapidly image and analyze perfused tissue culture cells in multiple fluorescent colors and brightfield. |
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The Jackson Labs |
NSG™* and NSG™-SGM3* mice are a proven host for engraftment of human tumors or establishment of human immunity following hematopoietic stem cell transplantation. Here, we provide evidence that NSG and NSG-SGM3 mice...(click for more) |
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BioStatus Limited |
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Swift Biosciences |
Next-generation sequencing (NGS) of bisulfite-converted DNA to detect methylation status with per-base resolution is currently restricted by input requirements, requiring at least 50 ng of DNA. This Application Note shows how the unique chemistry of the Accel-NGS® Methyl-Seq DNA Library Kit enables the construction of high complexity libraries for ....(click for more) |
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TTP Labtech |
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BioTek |
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Agilent Technologies |
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Agilent Technologies |
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Agilent Technologies |
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Agilent Technologies |
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INTEGRA |
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Jackson Labs |
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Trevigen |
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EMD Millipore |
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Jackson Labs |
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EMD Millipore |
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Thermo Fisher
Invitrogen
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Many biological science applications require an accurate, precise measurement of the number of cells and their viability prior to downstream analysis. This assessment
can be done manually with a traditional hemocyotmeter and microscope or with an automated cell counter, such as the Invitrogen™ Countess™ II FL. |
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ProteinSimple |
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EMD Millipore |
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Jackson Labs |
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IN TEGRA
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For the vast number of scientists that undertake handheld pipetting protocols - INTEGRA has produced a highly informative illustrated 'Best Practices' guide. Drawing upon decades of pipetting experience - INTEGRA has compiled an unbiased series of hints and tips to help you improve your handheld pipetting. Expert advice is provided in areas including before you start, how to pipette and optimising pipetting performance. Each area of best pipetting practice discussed is backed up with an explanation of why this produces optimal results. |
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Gilson |
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TREVIGEN |
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Register for the Illumina Genomics Symposium
Next-Generation Sequencing Applications for Neurological Disorders
Today, cell biologists are looking to new methods, like next-generation sequencing, to investigate the genetic underpinnings of disease biology and generate hypotheses for further studies that analyze gene expression and protein function. |
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New paper
Breaking the Bottleneck: Boosting Lab Performance with Automated Plate Seal Removal
Removing and/or replacing hundreds of plate seals at a time can represent a formidable and painstaking challenge. This paper reviews how high-throughput screening (HTS) and high-content screening (HCS) laboratories discovered hidden productivity improvements using new adhesive-based de-sealing technology. |
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GenScript |
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TREVIGEN |
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Quanterix Corporation |
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Bio-Rad Laboratories |
The story of Leukemia research is being re-written—one droplet at a time. See how droplet digital PCR gives scientists the power to detect what was previously undetectable. Watch Video |
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Eppendorf
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BioTek Instruments, Inc.
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Quanterix Corporation
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ATCC
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BioTek Instruments
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Eppendorf
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SDIX®
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Mirus Bio, LLC
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Singulex
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Hamilton Company
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Applied Photophysics Ltd
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Waters
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To decrease the frequency of system repairs and contamination, a series of steps have been outlined for maintenance and care of a chromatographic system and columns used for the analysis of biomolecules.
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AMRI
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Waters Corp.
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Gilson, Inc
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INDIGO Biosciences, Inc.
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Shimadzu Scientific Instruments
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Gilson, Inc
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Bio-Rad Laboratories
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Applied Photophysics Ltd
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BIOSEARCH TECHNOLOGIES
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InhibOx
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JMP Clinical |
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Lucigen Corporation
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EMD Millipore
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DiscoveRX
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INDIGO Biosciences
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SABiosciences, a QIAGEN company
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Trevigen, Inc
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DiscoveRX
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Caliper Discovery Alliances & Services
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SABiosciences, a QIAGEN company
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Invitrogen by Life Technologies
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Accuri Cytometers, Inc.
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Invitrogen by Life Technologies
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Trevigen, Inc.
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Back West, Inc. and Jumpstart Biodevelopment
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Adeptia Inc.
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