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MicroRNA Assay for Gene Expression Profiling
November 2007
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Illumina Inc.  recently launched a microRNA assay for gene expression profiling. Priced at $95 per sample, this assay is the only solution available to allow rapid and reproducible miRNA expression profiling at a price less than half that of other commercially available methods. By developing a high-density expression array with content from the miRBase Sequence Database this new tool will help researchers better understand the role microRNAs (miRNA) play in regulating mRNA. Compared to traditional mRNA-based gene expression approaches, miRNA profiling has distinct advantages: A single miRNA can regulate the expression of several genes and could produce larger effects that more clearly influence a disease state. With only approximately 1,000 miRNAs predicted in humans, compared to 30,000 mRNAs per cell, miRNAs represent a rich pool of potential diagnostic biomarkers. In addition, miRNAs are less likely to be degraded in formalin-fixed, paraffin-embedded samples or other RNA samples of poor quality.
Illumina Inc.
800-809-4566

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