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KDRI large protein content now included with Promega HaloTag vectors
Promega Corp., in conjunction with Kazusa DNA Research Institute (KDRI) in Chiba Prefecture, Japan, will soon offer vectors encoding Promega HaloTag with genetic content from KDRI's catalog. The KDRI content derives from large, typically difficult-to-clone human genes. In addition, there will be a comprehensive catalog of human transcription factors commonly used in research and drug discovery. As a result, researchers can gain ready access to the multi-functional HaloTag fused to these larger proteins. The initial offering encompasses more than 1900 KDRI ORF clones in Promega Flexi vector. It includes the coding sequence for HaloTag, a multi-functional protein tag that can be used for cellular imaging as well as protein purification and immobilization. Promega will soon launch protein arrays for functional studies that utilize HaloTag covalent binding properties for binding proteins to glass slides, while cellular imaging with fluorescent ligands to HaloTag is well established. The first vectors will be available at the start of 2009 through KDRI (http://www.kazusa.or.jp/kop/) and will be distributed globally.