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Improved efficiency of intracellular delivery of bioactive molecules
September 2009
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Biocompatibles UK Ltd.  
 
Biocompatibles has launched a new product in its CelLuminate range of intracellular delivery systems. The new CelLuminate Vesicle-forming Polymer System (VPS) improves the efficiency of intracellular delivery of bioactive molecules compared to conventional liposomal systems. It can deliver anything from fluorophores to RNA, DNA and proteins efficiently and with minimal cytotoxic effects. CelLuminate is made from proprietary biomimetic copolymer and exploits the natural cellular endocytotic pathways. As the surface chemistry of the vesicles mimics that of cell membranes, the rate and amount of vesicles endocytosed is orders of magnitude higher than conventional liposomal systems. Being pH-sensitive, the CelLuminate vesicles utilize the pH drop in the endosome to deliver the desired payload into the cell cytosol. CelLuminate VPS is designed so that researchers can prepare their own vesicles to encapsulate any bioactive agent, easily and without experience.  
 
Biocompatibles UK Ltd.
www.celluminate.com
+44 (0)1252 732 671 


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