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Root to stem
August 2011
EDIT CONNECT
SHARING OPTIONS:
In our first survey
collaboration with Mizuho Securities USA Inc.,
the
picture for biopharma research and development and for stem cells specifically
is definitely a mixed bag—at least for the United States.
Perhaps it's just skittishness in a still-shaky economy, and thus the
feeling that things are worse
here in the States than they are elsewhere and
won't get better, but it is interesting to see among the 99 respondents to the
"Mizuho Drug Discovery
R&D and Stem Cell Survey"—all U.S.-based and 80
percent of them either in the biopharmaceutical industry or academia—they seem
modestly hopeful
about stem cells in general, but are a little more grim on
U.S. competitiveness and funding.
Looking at 2011, nearly 40 percent of respondents saw funding as being
on a downward trend compared to 2010, though a quarter of them believe
funding
is up. Predicting the 2012 vs. 2011 dynamic, things are a bit more even, with
36 percent saying funding will be up and 34 percent saying it
will be down.
However, the 12-month outlook for R&D funding in the stem cell
realm has a
decidedly more positive spin, with respondents expecting
mid-single-digit growth. Moreover, 47 percent expected stem cell research to be
among the
areas that will see the largest funding increases, beat out only by
cancer, which 52 percent predicted will see some of the biggest boosts. Coming
in
slightly behind stem cell research in terms of confidence that funding will
increase were biomarker research, cited by 37 percent of respondents, and
personalized medicine, cited by 36 percent. Around 20 percent of respondents
saw one or more of the following research areas as being among the big
gainers:
diabetes, neurosciences, nanotechnology and vaccines.
Respondents were far less confident
about areas like infectious
disease, autoimmune disorders, genomics, disease prevention, immunology,
proteomics, metabolic disease, women's health and
synthetic biology. Scoring
dead last, with fewer than 5 percent expected funding boosts in the next year,
was the area of association studies.
Nearly half of respondents think the current political climate is
conducive for stem cell research and just under a quarter have neutral
feelings.
More striking is that approximately 71 percent believe that the
current climate is getting better for
stem cell research—though not a single
respondent "strongly agreed" with that
view.
But while the climate may be improving, respondents
aren't so sure the
United States will be a major beneficiary in any stem cell windfalls.
Respondents were split on the statement that U.S. stem cell
research will lag
the rest of the world due to political restrictions, as 35 percent somewhat
agree with that and 41 percent somewhat disagree—though
on average, the
response score was a neutral 3.2 on a scale of 1 to 5.
This isn't far off from
opinions of U.S. competitiveness overall, as
the survey shows that respondents tend to think that the Unites States is
losing its R&D edge, with a
slightly above neutral score of 3.5—1 being
"strongly disagree" and 5 being "strongly agree." Also, respondents tended to
believe that pharma is
losing its competitive edge versus biotech (3.5), and
focusing more on product development (3.4). Also, respondents modestly agree
(3.4) that China
will start to dominate R&D this decade. Views on Europe
losing its competitive R&D edge were more neutral (3.0) as was the view on
research
being de-emphasized at respondents' organizations (2.9).
So, in the end, regardless of whether the
United States dominates, lags
or hovers in the middle, when will stem cell therapeutics become the standard?
Weighing responses overall, the general
opinion seems to be between 12 and 13
years, with more than a quarter predicting it will happen within the next five
to 10 years and just under 50
percent predicting within the next 10 to 20
years. Neurological care is expected to be the most important indication for
stem cell therapy, though
oncology, cardiovascular and allergy and immunology
also fared well in respondents' predictions, trailed by metabolic disease,
endocrinology and
women's health.
Editor's Note: If you are
interested in obtaining a copy of this
survey, please contact Peter Lawson at Mizuho Securities at
peter.lawson@us.mizuho-sc.com.
ALSO FROM OUR
AUGUST ISSUE SPECIAL REPORT:
Researchers discuss the ethical, moral and scientific concerns
associated with stem cell research
By Amy Swinderman, ddn Chief Editor Editorial: Embryonic stem cell research: A Dickey-Wicker of a situation
Isn't it about time Congress revisited what is essentially an afterthought on a 15-year-old appropriations bill, clearly articulated the facts and concerns about hESC research and put forth a specific policy on the matter? By Amy Swinderman, ddn Chief Editor Code: E081132 Back |
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