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Tissue-specific conditional gene knockout in rats
May 2012
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Sigma-Aldrich (SAGE Labs)  
 
Sigma Advanced Genetic Engineering (SAGE) Labs, an initiative of Sigma Life Science, announces the successful extension of its CompoZr Zinc Finger Nuclease technology, allowing it to achieve the first tissue-specific conditional knockout of an endogenous gene in rats. As rats are more predictive of human conditions than mice in terms of physiology, neurobiology and other aspects, the new approach has significant benefits for researchers. Rats engineered with tissue-specific conditional gene knockouts are available through the SAGEspeed Custom Model Development Service.
 
 
 
Sigma-Aldrich (SAGE Labs)
(314) 286-7810

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