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Novavax RSV vaccine found effective in baboons
November 2014
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GAITHERSBURG, Md.—Novavax Inc. recently shared preclinical data regarding its respiratory syncytial virus (RSV) vaccine in baboons at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy in Washington, D.C. The study found that immunizing pregnant baboons in the third trimester with Novavax’ RSV F-protein nanoparticle vaccine caused them to generate anti-F IgG antibodies that were transferred to their newborn babies, and infants born to these immunized mothers demonstrated protection from RSV challenge comparable to that seen from palivizumab therapy. Novavax collaborated with the University of Oklahoma on this study.
 
Dr. Greg Glenn, senior vice president of research and development at Novavax, noted that “This study adds to substantial evidence and validation supporting our RSV maternal immunization strategy as we move towards the initiation of our first study in pregnant women in the next few months.”
 
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