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Traumeel-Zeel therapy provides osteoarthritis pain relief
January 2015
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MANCHESTER, N.H.—A recent study has found that co-administration of Traumeel (Tr14) and Zeel (Ze14) intra-articular (IA) injections represents a safe, effective treatment for moderate-to-severe pain associated with knee osteoarthritis versus IA placebo. The lead investigator was Dr. Carlos J. Lozada, professor of clinical medicine, University of Miami Miller School of Medicine. Randomized patients with moderate-to- severe chronic knee OA received three weekly IA injections of either Tr14 and Ze14 or saline, with a primary efficacy variable of change in knee pain from baseline to end-of-study, measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). By day 15, patients receiving the Tr14-Ze14 combination treatment saw significant reductions in pain, and secondary endpoints—total WOMAC and subscores for stiffness and physical function, change in pain following a 50-foot walk and patient and physician assessments—were directionally consistent. No serious adverse events were reported.

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