In The Spotlight
DDNews Cancer Research Exclusive
 
 
Recent work with nanoparticles offers a new approach to photo-thermal cancer therapies
 
(Photo credit: University of Toronto)
 
The PEARLs (Photothermal Enhancing Auto-Regulated Liposomes) were developed by Dr. Gang Zheng of the Princess Margaret Cancer Centre and University of Toronto and colleagues, who say they overcome traditional roadblocks to penetrate deeper into tumors.
 
 
NEWS
A pair of new deals with Daiichi and Takeda help move Thermo’s technology forward
 
Minimally invasive test provides early breast cancer detection
 
NucleoBio Inc. is advancing a new diagnostic, Prostac, which it hopes will enable users to determine between indolent and aggressive prostate cancer
 
CrownBio launches new humanized model, enters strategic partnership with Phanes and presents many posters at AACR 2018
 
First-in-class EZH2 inhibitor demonstrates safety and efficacy
 
Nanobiotix and Weill Cornell Medicine enter research collaboration
 
Sutro Biopharma advances STRO-001 and STRO-002 into the clinic against multiple cancer types
 
Aptevo and Alligator present preclinical data for novel immunotherapy bispecific candidate
 
  
FEATURES
(Photo credit: NCI, NIH)
 
 
The latest Annual Report to the Nation shares that cancer survival rates are rising, while incidence and death rates are on a downward trend
 
OPINION
CAR-T Next Generation Immunotherapy: Better Targeting, New Approaches
by Dr. Eyal Talor, CEL-SCI
A look at what to expect from the second generation of cancer immunotherapies, after the progress--and pitfalls--of CAR-T cell therapies

Guest Commentary: Planning successful oncology trials amid a rapidly shifting treatment landscape
by JK Bryan & A Zupnick, Novella
When it comes to oncology clinical trials, drug developers need to stay abreast of the rapidly evolving and competitive landscape while also remaining flexible and innovative in responding to these changes

Enhancing Immuno-Oncology with RNA Interference
by Dr. Alexey Eliseev, RXi
The “War on Cancer” declared by the National Cancer Act of 1971 proceeded through a series of evolutionary developments in chemotherapy, radiation treatments and targeted therapies, but until recently was only marginally successful in extending the lives of late-stage cancer patients. A major breakthrough has been achieved over the last decade with the development of immunotherapeutic treatments that empower a patient’s own immune cells to destroy tumors

 
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