|
Tools to study genomic instability and genotoxic stress
October 2010
SHARING OPTIONS:
Trevigen Inc.
Trevigen Inc. has announced the availability of 19 DNA
repair gene-knockdown cell lines, encompassing the Base Excision
Repair
pathway. These are target specific LN428 glioblastoma shRNA lentivirus
transduced cells that are rigorously qualified and mycoplasma-free.
Knockdown
levels range from 75 percent to 98 percent as determined by RT-PCR. Lentiviruses
are maintained by puromycin selection. DNA repair proteins
maintain the
stability of the genome. When repair protein function is impaired through
mutations, the genome may become unstable—a hallmark of solid
tumors. The
availability of this panel of knockdown cell lines will permit scientists to
study the molecular etiology of tumor genomic instability and
to exploit it in
oncology research.
Trevigen Inc.
(800) 873-8447
www.trevigen.com Back |
Home |
FAQs |
Search |
Submit News Release |
Site Map |
About Us |
Advertising |
Resources |
Contact Us |
Terms & Conditions |
Privacy Policy
|